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Article : Paracetamol Dangerous to Cats
Article title : Paracetamol Dangerous to Cats

Paracetamol Dangerous to Cats

Cats are very prone to intoxication medicines, such as acetaminophen / paracetamol, anti-inflammatory drugs, or fever. Even in low doses though! Many brands of human medicine containing paracetamol / acetaminophen, especially the kind of hot-lowering drugs. Like, Bodrex, Tempra, biogesic, Panadol, sanmol, paracetamol, Poldan, etc. Never give these drugs in cats. Drug intoxication can cause death of the cat.


Glucuronyl transferase enzyme. Most of the enzyme that breaks down drugs found in the liver or liver. One named glucuronyl transferase enzyme molecules attach glucuronide duty on drug molecules and make it active so it can be excreted through the kidneys through urine. And the cat is one of the species with the amount of enzyme glucuronyl transferase very little. Therefore, drugs that use this enzyme, can not be removed completely through the kidneys. These drugs tend to remain active, accumulates in the bloodstream and cause organ damage.

Methemoglobinemia. In excessive doses, paracetamol can cause damage and death of liver cells in dogs. Whereas in cats causes metabolic disorders of hemoglobin which is often called methemoglobinemia. Methemoglobin is a form of hemoglobin that can not bind and transport oxygen. Excessive methemoglobin in the blood results in the blood can not carry oxygen cat, the cat's body become starved of oxygen, the heart beats faster, panting breath, and mucous membranes begin to dark brown. Further it can cause death.

Paracetamol poisoning cats mark, usually appear 1-4 days after administration: Saliva dripping excess (hypersalivation), abdominal pain, mucous membranes are brown-gray, panting breath, swelling (on the face, neck and legs), low body temperature , footsteps uncoordinated, dark brown urine, vomiting, depression, yellow body.
Treatment. Giving oxygen, infusions and drugs such as acetylcysteine ​​and vitamin C. In addition to the amino acid Cysteine ​​can be given. This amino acid is necessary so that the liver can repair damaged cells.

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